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LDHB KD significantly downregulated GSH synthesis genes, such as glutamate-cysteine ligase (GCL) catalytic and modifier subunits (GCLC and GCLM), GSH synthetase (GSS), and GSH reductase (GSR), as well as the GSH gene signature ( Figure 1f
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In summary, BPC-157 and TB-500 are structurally distinct compounds from different biological origins
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