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MOTS-c appears to be secreted by contracting muscle mitochondria in response to metabolic stress, and may mediate some of exercise's systemic metabolic benefits: AMPK activation in liver and adipose tissue, improved insulin-stimulated glucose uptake, and upregulation of genes involved in fatty acid oxidation
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Busulfan Busulfan is an alkylating agent widely used in myeloablative conditioning regimens before bone marrow or hematopoietic stem cell transplantations 78
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