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4), which identified 'air embolism' as the highest severity issue for loose connections," FDA wrote

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The animal literature, reviewed by Sikiric and colleagues (Current Pharmaceutical Design 2018), describes vascular recruitment and cytoprotective effects, and one rat spinal cord injury study reported improved tail motor function and resolution of spasticity by day 15 (Journal of Orthopaedic Surgery and Research 2019, PMID 31266512)