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In a study, 600 mg of oral NAC twice daily significantly reduced the occurrence of flu symptoms, with only 25% of infected individuals showing symptoms compared to 79% in the placebo group, highlighting its potential in reducing respiratory infections like COVID-19 [52]

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Heightened systemic inflammatory states appear to worsen COVID-19 outcomes by initiating a counter-regulatory response, which includes the upregulation of levels of the ACE2 receptor and its associated peptidases 11