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CEP63, a protein that interacts with CEP152 83 , the loading partner of PLK4, was reported to bind the selective autophagy receptor p62, although the mechanism by which CEP63 might activate selective autophagy 84 remained unclear

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This crucial phase of the malady, in analogy with other viral infections and to a widely accepted pharmacological praxis, should be timely treated either with etiotropic drugs (which in COVID-19 case are still lacking) as well as with host-directed agents to manage/prevent the symptoms (Kaufmann et al., 2018)