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MOTS-C represents a distinct category among the best peptides for weight loss research as a mitochondrial-derived peptide (MDP) encoded within the 12S rRNA region of the mitochondrial genome, first identified as a regulator of metabolic homeostasis by Lee and colleagues

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Some medical conditions, including autoimmune disease like shingles (herpes zoster), rheumatoid arthritis or celiac disease, as well as Lyme disease, some cancers, and several other diseases can also cause or increase the risk of nerve damage, also sometimes referred to as peripheral neuropathy